GMP Factory Supply Valsartan 99% Powder CAS 936623-90-4

• CAS No.: 936623-90-4
• Shelf Life: 3 Years
• Grade: Pharmaceutical Grade
• Standard: GMP
• Purity: 99%
• Product Name: Sacubitril Valsartan
• Transport Package: Carton
• Specification: BP/USP/EP/JP
• Trademark: Dijia
• Origin: Shandong China
• Production Capacity: 10000kg/Month

Product Description

GMP Factory Supply Valsartan Sacubitril 99% Powder CAS 936623-90-4 

 

Product Description

 

roduct Name	Factory Supply Valsartan Sacubitril Powder CAS 936623-90-4 Valsartan Sacubitril  For Pharmaceutical Intermediate
Appearance	powder
cas	936623-90-4
Assay	99%
Keywords	Valsartan Sacubitril;Valsartan Sacubitril Powder;Valsartan Sacubitril CAS 936623-90-4
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

What is Valsartan Sacubitril? LCZ696 is a dual angiotensin II receptor antagonist and neprilysin inhibitor that is a combination of the nonpeptide angiotensin II receptor antagonist valsartan (Item No. 14178) and AHU377 (Item No. 21473), a prodrug of LBQ657 (Item No. 19829), which is an inhibitor of the zinc metallopeptidase neprilysin., LCZ696 (2-60 mg/kg) induces a dose-dependent decrease in mean arterial pressure in rats expressing human renin and angiotensinogen, a double-transgenic model for angiotensin II-dependent hypertension. Formulations containing LCZ696 are under clinical investigation for the treatment of mild to moderate hypertension and chronic heart failure.

Function of Valsartan Sacubitril
 

LCZ696, a first-in-class inhibitor of dualacting angiotensin-2 type-I receptor and neprilysin inhibitors, was developed as a molecule composed of molecular moieties of valsartan and neprilysin inhibitor prodrug AHU377 in a 1:1 ratio. Several phase 2 randomised clinical trials have been done or are underway in patients with hypertension. In a proof-of-concept randomised trial, LCZ696 was compared with valsartan in 1328 patients with mild-to-moderate hypertension, and provided fully additive reduction of blood pressure. No cases of angio-oedema were reported in the 8 week treatment period. This tolerance should be confirmed, particularly in black patients, for whom omapatrilat resulted in a higher occurrence of angio-oedema than in white patients. Indeed, in the proof-of-concept trial only about 8% of patients were black.

MDL number  :LU20160179

 

Superiority

We are the GMP manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request. 
 

Our service

1. Reply your inquiry in 24 working hours.
2. Customized design is available. OEM are welcomed.
3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
staff.
4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

 

 

 

 

 

  

 

 

 

Product Details

 

 

our company 


 Hebei xianri biotechnology co.,ltd mainly focusing on dietary supplements processing in China, providing wide range of natural products with different forms including softgel, tablet, Capsules, vegetables hard capsules, powder and gummy. our R&D department providing value-added OEM and private label services for you.

Our company covers an area of 8 hectares and we have over 600 workers and staff members ,we owns five dietary supplement processing factories and two marine raw material extracting factories , which have passed the quality management certifications of GMP cGMP,HACCP,U.S.FDA,ISO9001,ISO14001,OHASAS18001 and BRC for global retails. We have imported 18 large soft gel production lines and more than 20 pieces of production equipment, such as fully automatic tablet compressing machines, hard capsule filling machines,3D mixers and coating machines, our daily production capacity of 20 million pieces of nutritional supplements and more than 1200 health products , bottling capability of 150 thousand bottles. We are largest production base of dietary supplements in Asia.

FAQ
How to contact us:
 
 
 
Address: No.392 Huaibei Road,Yuhua Districe, Shijiazhuang,China.
Our Payment Terms: 
Payment terms: 30% TT in advance as deposit for us to start the production, and the balance should be
TT after the shipment and before the seller release the Original B/L to buyer. 

Q: When can I get the price?
A: We usually quote within 24 hours after we get your inquiry.
If you are very urgent to get the price, please tell us so that we will regard your inquiry priority.
Q: How can I get a sample to check your quality?
A: After price confirmation, we are happy for sending samples in 2 days to you once you need.
Q: What about the lead time for mass production?
A: Honestly, it depends on the order quantity and the season you place the order. Always 1 month.
Q: What is your terms?
A: W accept EXW, FOB, CFR, CIF, DDU, DDP, etc. You can choose the one which is the most
convenient or cost effective for you.


To get more information, just feel free to contact with us. 
Sincerely looking forward to your cooperation.