FDA Cos GMP Certificated Fondaparinux Sodium Raw Materials Cardiovascular

• Shelf Life: 3 Years
• Grade: Food Grade. Pharmaceutical Grade
• CAS No.: 114870-03-0
• DMF: 030767
• Transport Package: Carton
• Origin: China
• Model NO.: APIs
• HS Code: 2934990002
• Production Capacity: 150000000 Ton

Product Description

FDA COS GMP certificated Fondaparinux sodium raw materials cardiovascular CAS No.114870-03-0

Product Details
Product Name: Fondaparinux sodium
Synonyms: Fondaparin SodiuM;Methyl O-2-Deoxy-6-O-sulfo-2-(sulfoaMino)-α-D-glucopyranosyl-(14)-O-β- D-glucopyranuronosyl-(14)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoaMino)-α-D-glucopyranosyl-(14)-O-2-O-sulfo-α-L-idopyranuronosyl-(14)-2-deoxy-2-(sulfoaMino)-α-D-glucopyranoside 6-(Hydrogen Sulfate) DecasodiuM Salt;Fondaparinux SodiuM Identification
CAS: 114870-03-0
MF: C31H43N3O49S8.10Na
MW: 1728.08
EINECS: 686-283-7

Melting point: 96-97°C
Boiling point: 329.1±15.0 °C
Density: 1.137±0.06 g/cm3
Storage temp.: -70°C
Appearance: White Powder

Description:

Fondaparinux sodium was first introduced in the US for prophylaxis of deep vein thrombosis which may lead to pulmonary embolism following major orthopaedic surgery. Fondaparinux is the first of a new class of antithrombic agents distinct from low molecular weight heparin (LMWH) and heparin. This entirely synthetic molecule is a copy of the heparin pentasaccharide sequence, the shortest fragment able to catalyze antithrombin lllmediated inhibition of factor Xa thereby inhibiting thrombin generation without antithrombin action. Fondaparinux does not display significant effects on coagulation tests (such as activated partial thromboplastin time and prothrombin time), does not bind to platelet factor 4 or promote heparin-induced thrombocytopenia. In phase III studies, fondaparinux significantly reduced the incidence of thromboembolism following orthopedic surgery, with an overall risk reduction of 50% in comparison to the LMWH, enoxaparin. Following subcutaneous administration, fondaparinux has a nearly complete bioavailability, a rapid onset of action, a prolonged half-life (17.2 h) enabling once daily dosing and is not metabolized preceeding renal excretion. The drug appears to be generally safe, with haemoragic complications either comparable to or higher than those for LMWH.

Uses:

Synthetic pentasaccharide corresponding to the anti-thrombin binding site of heparin. Anti-thrombotic.

 

 

 

 

 

 

our company 


 Hebei xianri biotechnology co.,ltd mainly focusing on dietary supplements processing in China, providing wide range of natural products with different forms including softgel, tablet, Capsules, vegetables hard capsules, powder and gummy. our R&D department providing value-added OEM and private label services for you.

Our company covers an area of 8 hectares and we have over 600 workers and staff members ,we owns five dietary supplement processing factories and two marine raw material extracting factories , which have passed the quality management certifications of GMP cGMP,HACCP,U.S.FDA,ISO9001,ISO14001,OHASAS18001 and BRC for global retails. We have imported 18 large soft gel production lines and more than 20 pieces of production equipment, such as fully automatic tablet compressing machines, hard capsule filling machines,3D mixers and coating machines, our daily production capacity of 20 million pieces of nutritional supplements and more than 1200 health products , bottling capability of 150 thousand bottles. We are largest production base of dietary supplements in Asia.

FAQ
How to contact us:
Sarah
 
 
Address: No.392 Huaibei Road,Yuhua Districe, Shijiazhuang,China.
Our Payment Terms: 
Payment terms: 30% TT in advance as deposit for us to start the production, and the balance should be
TT after the shipment and before the seller release the Original B/L to buyer. 

Q: When can I get the price?
A: We usually quote within 24 hours after we get your inquiry.
If you are very urgent to get the price, please tell us so that we will regard your inquiry priority.
Q: How can I get a sample to check your quality?
A: After price confirmation, we are happy for sending samples in 2 days to you once you need.
Q: What about the lead time for mass production?
A: Honestly, it depends on the order quantity and the season you place the order. Always 1 month.
Q: What is your terms?
A: W accept EXW, FOB, CFR, CIF, DDU, DDP, etc. You can choose the one which is the most
convenient or cost effective for you.


To get more information, just feel free to contact with us. 
Sincerely looking forward to your cooperation.